The stage is set for a new natural order in the way we diagnose disease. However, we must ensure that these new clinical work flows are implemented safely. In a world that is increasingly virtual, data privacy is of the utmost importance. New ethical standards must be implemented to bring Hippocrates into the 21st century, as exemplified by the recent multidisciplinary effort to develop Stanford’s “Guiding Principles for Ethics in Digital Health” . True to the core of medicine, patients and their safety must come first.